Palm
نخل
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Wikipedia) - Paralemmin is a protein that in humans is encoded by the PALM gene. This gene encodes a member of the paralemmin protein family. Other members of this family include C
AP-23, GAP-43, MARCKS, and MacMARCKS. The product of this gene is a prenylated and palmitoylated phosphoprotein that associates with the cytoplasmic face of plasma membranes and is implicated in plasma membrane dynamics in neurons and other cell types. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. PALM For company with same NASDAQ symbol, see Palm,_Inc.. For microscopy technique, see Super resolution microscopy#Photoactivated localization microscopy (PALM) and Fluorescence Photoactivation Localization Microscopy (fPALM).
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Paralemmin
Identifiers
Symbols | PALM; KIAA0270 |
External IDs | OMIM: 608134 MGI: 1261814 HomoloGene: 1937 GeneCards: PALM Gene |
Gene Ontology Molecular function | • protein binding • D3 dopamine receptor binding | Cellular component | • plasma membrane • integral to plasma membrane • cytoplasmic membrane-bounded vesicle • basolateral plasma membrane • apicolateral plasma membrane • axon • filopodium membrane • dendritic spine | Biological process | • cellular component movement • cytoskeleton organization • negative regulation of adenylate cyclase activity • regulation of cell shape • positive regulation of filopodium assembly • synapse maturation • negative regulation of dopamine receptor signaling pathway • positive regulation of dendritic spine development • cellular response to electrical stimulus • protein targeting to plasma membrane | | Sources: Amigo / QuickGO | |
RNA expression pattern
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| More reference expression data |
Orthologs
Species | Human | Mouse | |
Entrez | 5064 | 18483 | |
Ensembl | ENSG00000099864 | ENSMUSG00000035863 | |
UniProt | O75781 | Q9Z0P4 | |
RefSeq (mRNA) | NM_001040134.1 | NM_001161747.1 | |
RefSeq (protein) | NP_001035224.1 | NP_001155219.1 | |
Location (UCSC) | Chr 19: 0.71 – 0.75 Mb | Chr 10: 79.79 – 79.82 Mb | |
PubMed search | | |
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Paralemmin is a protein that in humans is encoded by the PALM gene.
This gene encodes a member of the paralemmin protein family. Other members of this family include CAP-23, GAP-43, MARCKS, and MacMARCKS. The product of this gene is a prenylated and palmitoylated phosphoprotein that associates with the cytoplasmic face of plasma membranes and is implicated in plasma membrane dynamics in neurons and other cell types. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
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